What does “-less” mean at the end of a word?

The suffix “-less” usually means “without,” “lacking,” or “free from” something. For example, fearless means “without fear,” while painless means “without pain.”

Is “-less” a prefix or a suffix?

“-Less” is a suffix because it appears at the end of a base word. A prefix appears at the beginning of a word, while a suffix appears at the end.

Are all Words Ending In Less negative?

No, not all Words Ending In Less have negative meanings. Some words describe positive qualities. For example, fearless means brave, selfless means caring about others, and flawless means perfect or without mistakes. However, words such as careless , heartless , and hopeless usually express negative meanings.

What are some positive words ending in “-less”?

Some positive words ending in “-less” include: Fearless Selfless Flawless Tireless Effortless Priceless Timeless Limitless These words often describe courage, kindness, beauty, value, or strong effort.

Are Words Ending In Less always adjectives?

Most Words Ending In Less are adjectives because they describe people, objects, feelings, or situations. For example: a fearless leader a wireless device a hopeless situation However, the exact role of a word can depend on how it is used in a sentence.

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isomerase

noun

an enzyme that catalyzes its substrate to an isomeric form

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Word Facts

Word length: 9
Starts with: I
Ends with: E
Contains: SO
Scrabble score: 11
Database source: OEWN 2025 Core

How it sounds

Pronunciation

aɪˈsɒməˌɹeɪz

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Meaning

Definitions

noun

an enzyme that catalyzes its substrate to an isomeric form

isomerase

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